Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770570 | 0.86 | BACE1 (0.76) | BACE1SMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL9770475 | 0.85 | BACE1 (0.53) | BACE1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9770581 | 0.85 | ALDH1A1 (0.48) | BACE1ALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL9770540 | 0.84 | BACE1 (0.54) | BACE1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL9770505 | 0.82 | BACE1 (0.44) | BACE1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7270186 | 0.80 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9770401 | 0.80 | BACE1 (0.67) | BACE1ALDH1A1MAPK1LMNAPTGS1 | |
| SCHEMBL9770149 | 0.80 | BACE1 (0.67) | BACE1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9770412 | 0.80 | BACE1 (0.67) | BACE1SMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL9770562 | 0.80 | BACE1 (0.67) | BACE1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |