Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770481 | 0.84 | BACE1 (0.60) | BACE1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL9770475 | 0.82 | BACE1 (0.53) | BACE1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL9770570 | 0.80 | BACE1 (0.76) | BACE1PPARDMAPTLMNAPTGS1 | |
| SCHEMBL9770444 | 0.79 | BACE1 (0.64) | BACE1PPARDPTGS1SLC6A2KMT2A | |
| SCHEMBL9770505 | 0.79 | BACE1 (0.44) | BACE1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL9269272 | 0.78 | TSHR (0.48) | ALDH1A1GAAMAPTLMNAL3MBTL1 | |
| SCHEMBL9770439 | 0.76 | BACE1 (0.60) | BACE1PPARDPTGS1SLC6A2HTT | |
| SCHEMBL9770377 | 0.76 | BACE1 (0.67) | BACE1RAB9A | |
| SCHEMBL9770406 | 0.76 | BACE1 (0.60) | BACE1PPARDMAPTLMNAPTGS1 | |
| SCHEMBL9770396 | 0.76 | BACE1 (0.59) | BACE1PPARDMAPTPTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |