Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770481 | 0.85 | BACE1 (0.60) | BACE1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9770536 | 0.82 | BACE1 (0.62) | BACE1NPC1CHRNB2CHRNA4KMT2A | |
| SCHEMBL9770540 | 0.82 | BACE1 (0.54) | BACE1NPC1KMT2AMAOBALDH1A1 | |
| SCHEMBL11241976 | 0.82 | CHRNB2 (0.56) | NPC1CHRNB2CHRNA4KMT2AMAOB | |
| SCHEMBL9770505 | 0.81 | BACE1 (0.44) | BACE1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9770438 | 0.79 | TSHR (0.59) | BACE1TSHRMAPTADRB3 | |
| SCHEMBL9770148 | 0.79 | BACE1 (0.58) | BACE1KMT2AMAOBALDH1A1TSHR | |
| SCHEMBL9770455 | 0.79 | BACE1 (0.58) | BACE1NPC1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL9770402 | 0.79 | BACE1 (0.58) | BACE1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9770581 | 0.79 | ALDH1A1 (0.48) | BACE1KMT2AMEN1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |