Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665859 | 0.79 | ALDH1A1 (0.56) | LMNAALDH1A1TDP1PKM | |
| SCHEMBL9770478 | 0.78 | SCN2A (0.54) | LMNAALDH1A1PKM | |
| SCHEMBL9770576 | 0.76 | GAA (0.58) | LMNAALDH1A1CA1CA2CA9 | |
| SCHEMBL10061451 | 0.75 | PTGS2 (0.43) | PTGS2SIGMAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL6228523 | 0.73 | MAPT (0.65) | PTGS2LTA4HPTGS1HRH3LMNA | |
| SCHEMBL8746688 | 0.73 | LMNA (0.58) | PTGS2LMNAALDH1A1CA1CA2 | |
| SCHEMBL31112913 | 0.72 | HTR2A (0.47) | PTGS2LTA4HPTGS1KDM4EALDH1A1 | |
| SCHEMBL11030316 | 0.72 | SCN2A (0.47) | ALDH1A1PKM | |
| SCHEMBL28049501 | 0.71 | LMNA (0.56) | PTGS2LMNAALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL10553766 | 0.71 | LMNA (0.56) | PTGS2LMNAALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |