Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770539 | 0.81 | ALOX12 (0.54) | POLBALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL41389 | 0.78 | CMA1 (0.70) | GAAPOLBALDH1A1HTTCMA1 | |
| SCHEMBL9770552 | 0.75 | RAB9A (0.71) | GAAPOLBRAB9AKMT2AATM | |
| SCHEMBL18825272 | 0.73 | NPC1 (0.64) | GAAPOLBALDH1A1LMNARAB9A | |
| SCHEMBL40778 | 0.71 | CMA1 (0.66) | GAAALDH1A1HTTCMA1KMT2A | |
| SCHEMBL11684109 | 0.71 | MEN1 (0.62) | GAAPOLBALDH1A1HTTCMA1 | |
| SCHEMBL12444397 | 0.71 | POLB (1.00) | GAAPOLBALDH1A1LMNARAB9A | |
| SCHEMBL9901831 | 0.71 | GAA (0.40) | GAAPOLBALDH1A1HTTLMNA | |
| SCHEMBL31175413 | 0.70 | GSK3A (0.53) | GAAPOLBALDH1A1HTTGSK3A | |
| SCHEMBL6535956 | 0.69 | LTA4H (0.58) | POLBALDH1A1HTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |