Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770696 | 0.81 | KEAP1 (0.52) | CES1HDAC8HDAC6FAAHALDH1A1 | |
| SCHEMBL1042453 | 0.79 | CES1 (1.00) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL5709778 | 0.79 | CES1 (1.00) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL10433444 | 0.76 | CES1 (0.70) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL13498524 | 0.76 | CES1 (0.70) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL1033375 | 0.76 | CES1 (0.64) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL16405134 | 0.76 | CES1 (0.70) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL9314779 | 0.76 | CES1 (0.70) | CES1PTPN1CES2AKR1B1PAM | |
| SCHEMBL6327762 | 0.75 | ALDH1A1 (0.49) | CES1PTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL11546063 | 0.74 | CES1 (0.52) | CES1PTPN1CES2AKR1B1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289390-B1 | PROCESS FOR ELIMINATING RADIOACTIVITY FROM EFFLUENTS BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1991-10-16 | — | — | EP | disclosed |
| US-5006254-A | Extraction with halogenated beta-diketone | RHONE-POULENC CHIMIE (FR) | 1991-04-09 | — | — | US | disclosed |
| EP-0289390-A1 | Process for eliminating radioactivity from effluents by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1988-11-02 | — | — | EP | disclosed |