Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770495 | 0.90 | KDM4E (0.44) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9770632 | 0.90 | KDM4E (0.44) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9770572 | 0.83 | KMT2A (0.44) | GAAKDM4ELMNAACHEHTT | |
| SCHEMBL9770550 | 0.74 | LMNA (0.46) | GAAKDM4EALDH1A1LMNAACHE | |
| SCHEMBL9171091 | 0.73 | ACHE (0.52) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9770657 | 0.73 | KDM4E (0.49) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9171496 | 0.69 | ACHE (0.50) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9770499 | 0.67 | KDM4E (0.45) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL10863962 | 0.66 | L3MBTL1 (0.61) | GAAKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL10286810 | 0.65 | ACHE (0.62) | GAAKDM4EALDH1A1HPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |