Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770632 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9770631 | 0.90 | GAA (0.46) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9770550 | 0.84 | LMNA (0.46) | KDM4EALDH1A1GAAELANELMNA | |
| SCHEMBL9770657 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9770499 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9770583 | 0.77 | CFTR (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9770572 | 0.74 | KMT2A (0.44) | KDM4EGAAELANELMNAMAPT | |
| SCHEMBL9770654 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9171091 | 0.71 | ACHE (0.52) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9770566 | 0.68 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | claimed |
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |