Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014908 | 0.91 | DHODH (0.40) | MMP13ALPGDHODHAKR1B1ICAM1 | |
| SCHEMBL9770670 | 0.84 | ALPG (0.55) | ALDH1A1HPGDALPGNPC1KDM4E | |
| SCHEMBL10696742 | 0.82 | MMP13 (0.38) | MMP13ALPGDHODHAKR1B1NPC1 | |
| SCHEMBL28345238 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDNPC1RXFP1TP53 | |
| SCHEMBL11397996 | 0.81 | AKR1B1 (0.37) | ALDH1A1HPGDMMP13ALPGDHODH | |
| SCHEMBL11014615 | 0.76 | ALPG (0.60) | ALDH1A1HPGDALPGDHODHKDM4E | |
| SCHEMBL11015093 | 0.71 | PTAFR (0.42) | — | |
| SCHEMBL11015097 | 0.70 | MEN1 (0.39) | ALDH1A1HPGDALPGL3MBTL1NPC1 | |
| SCHEMBL11018500 | 0.70 | ALPG (0.37) | ALPGAKR1B1MEN1KMT2A | |
| SCHEMBL11270745 | 0.69 | ALPG (0.67) | ALDH1A1HPGDALPGDHODHAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| US-4282360-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0027268-A2 | Quinazoline derivatives, process and intermediates for their preparation, medicaments containing them and their pharmaceutical use | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-22 | — | — | EP | disclosed |