Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 1.00 |
| ▸ | CA1 | P00915 | 11/20 | 1.00 |
| ▸ | CA2 | P00918 | 11/20 | 1.00 |
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11854383 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL2503956 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL11006542 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL31106380 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL6294034 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL8509938 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL229556 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL476380 | 1.00 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL237261 | 0.98 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| SCHEMBL15570905 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043070-A | Magnetic solvent extraction | BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 1991-08-27 | — | — | US | disclosed |
| US-4906382-A | Method of magnetizing nonmagnetic materials | BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4834898-A | SURFACTANTS | BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 1989-05-30 | — | — | US | disclosed |