Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770790 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL711850 | 0.77 | CES2 (0.48) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2699118 | 0.76 | CES2 (0.46) | LMNARAB9ANPC1MAPTHPGD | |
| SCHEMBL1115093 | 0.76 | CES2 (0.46) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8220499 | 0.75 | PLK1 (0.46) | ALDH1A1PLK1TAS1R3TAS1R1LMNA | |
| SCHEMBL709890 | 0.75 | CES2 (0.52) | ALDH1A1PLK1LMNATDP1RAB9A | |
| SCHEMBL13395492 | 0.75 | ALDH1A1 (0.50) | ALDH1A1PLK1CHRM2CYP2D6ADRA2B | |
| SCHEMBL3129690 | 0.75 | ALDH1A1 (0.59) | ALDH1A1PLK1CHRM2CYP2D6ADRA2B | |
| SCHEMBL523477 | 0.75 | TDP1 (0.48) | ALDH1A1ADRA2BKCNH2LMNASMN1; SMN2 | |
| SCHEMBL9565954 | 0.73 | TDP1 (0.47) | ALDH1A1ADRA2BKCNH2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289390-B1 | PROCESS FOR ELIMINATING RADIOACTIVITY FROM EFFLUENTS BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1991-10-16 | — | — | EP | disclosed |
| US-5006254-A | Extraction with halogenated beta-diketone | RHONE-POULENC CHIMIE (FR) | 1991-04-09 | — | — | US | disclosed |
| EP-0289390-A1 | Process for eliminating radioactivity from effluents by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1988-11-02 | — | — | EP | disclosed |