SCHEMBL9770982

SCHEMBL9770982

CC(C)Oc1cc(N(F)C(=S)N2CCCC=N2)ccc1Cl

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.32
PPOX P50336 2/20 0.31
PTGDR Q13258 1/20 0.30
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
HTR2A P28223 1/20 0.30
HTR7 P34969 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770973 0.74 PPOX (0.36) PPOX
SCHEMBL9770963 0.73 SLC6A3 (0.34)
SCHEMBL9836600 0.70 RORC (0.40) CCR1PTGDR
SCHEMBL10940947 0.64 MEN1 (0.44) PPOX
SCHEMBL19088276 0.61 CSNK2A1 (0.43) HTR1ADRD2HTR2AHTR7HTR6
SCHEMBL9836953 0.61 RORC (0.41)
SCHEMBL9835945 0.58 KCNQ3 (0.38)
SCHEMBL27433291 0.58 HSD17B10 (0.46)
SCHEMBL30954134 0.58 HSD17B10 (0.46)
SCHEMBL29954995 0.58 TTR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2191261-A None JP disclosed
US-5039331-A Condensed heterocyclic derivatives and herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1991-08-13 US disclosed
JP-H02191261-A THIOSEMICARBAZONE DERIVATIVE, ITS PRODUCTION AND HERBICIDE NISSAN CHEM IND LTD 1990-07-27 JP disclosed
EP-0304920-A2 Condensed heterocyclic derivatives, process for their production and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-03-01 EP disclosed