Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | PPOX | P50336 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940940 | 0.77 | PPOX (0.44) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9836600 | 0.70 | RORC (0.40) | MEN1KMT2AMAPK1ALDH1A1HPGD | |
| SCHEMBL9727578 | 0.69 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9727572 | 0.68 | KMT2A (0.49) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9727391 | 0.68 | MEN1 (0.47) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL8895085 | 0.67 | PPOX (0.54) | TSHRMAPK1RECQLALDH1A1KDM4E | |
| SCHEMBL5485208 | 0.67 | FKBP1A (0.63) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9727452 | 0.67 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9727251 | 0.67 | ALDH1A1 (0.45) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9727445 | 0.67 | TSHR (0.55) | MEN1KMT2ATSHRMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070389-B1 | 2-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL) HYDANTOINS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4437877-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |