Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771313 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9771382 | 0.84 | KMT2A (0.45) | ALDH1A1LMNASMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL9826664 | 0.81 | MAPT (0.39) | ALDH1A1LMNAMAPTACHEKDM4E | |
| SCHEMBL9771496 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTACHEKCNJ1 | |
| SCHEMBL9771377 | 0.70 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL9771342 | 0.67 | POLB (0.46) | ALDH1A1LMNAMAPTACHESMN1; SMN2 | |
| SCHEMBL9771326 | 0.66 | POLB (0.44) | ALDH1A1LMNAMAPTACHEKCNJ1 | |
| SCHEMBL9771317 | 0.64 | POLB (0.55) | ALDH1A1LMNAMAPTACHESMN1; SMN2 | |
| SCHEMBL4614544 | 0.62 | MGLL (0.67) | ALDH1A1LMNAMAPTGFERPOLB | |
| SCHEMBL8329627 | 0.61 | KDM4E (0.71) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068341-A | OPTICALLY ACTIVE HYDANTOINS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |