Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771335 | 0.82 | ADORA2A (0.48) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9771342 | 0.82 | POLB (0.46) | ALDH1A1HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL9826750 | 0.79 | MAPT (0.40) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9771326 | 0.79 | POLB (0.44) | ALDH1A1HTTLMNAMAPTKCNJ1 | |
| SCHEMBL9771317 | 0.71 | POLB (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9771316 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HTTLMNAMAPTKCNJ1 | |
| SCHEMBL16589756 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HTTLMNAMAPTKCNJ1 | |
| SCHEMBL10267429 | 0.66 | HDAC6 (0.56) | ALDH1A1HTTLMNAMAPTKCNJ1 | |
| SCHEMBL9771496 | 0.66 | ALDH1A1 (0.51) | ALDH1A1HTTLMNAMAPTKCNJ1 | |
| SCHEMBL4614544 | 0.65 | MGLL (0.67) | ALDH1A1LMNAMAPTKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068341-A | OPTICALLY ACTIVE HYDANTOINS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |