Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 14/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775281 | 0.88 | ALDH1A1 (0.46) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775263 | 0.87 | NAAA (0.39) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775300 | 0.86 | ACE (0.44) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9774191 | 0.83 | PREP (0.47) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775231 | 0.82 | ACE (0.54) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775291 | 0.81 | NAAA (0.38) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9774174 | 0.81 | ACE (0.52) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9774133 | 0.81 | PREP (0.47) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL9775269 | 0.79 | ACE (0.46) | FKBP1AACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775452 | 0.79 | ACE (0.68) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |