Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775268 | 0.88 | FKBP1A (0.47) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775291 | 0.85 | NAAA (0.38) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775235 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GLAHPGDACEMEN1 | |
| SCHEMBL9775263 | 0.81 | NAAA (0.39) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL4802081 | 0.80 | CYP3A4 (0.46) | ALDH1A1ACEMEN1KMT2ACYP3A4 | |
| SCHEMBL9775259 | 0.80 | ACE (0.51) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775231 | 0.79 | ACE (0.54) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL4800141 | 0.79 | FFAR2 (0.44) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773185 | 0.78 | ACE (0.68) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773177 | 0.78 | ACE (0.73) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |