Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL29061129 | 0.95 | ALDH1A1 (0.45) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL28861161 | 0.95 | ALDH1A1 (0.43) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL29061142 | 0.95 | ALDH1A1 (0.43) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL7567172 | 0.95 | ALDH1A1 (0.43) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL7941570 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL20954078 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL1168962 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL20954075 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL5712918 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCA4TP53LMNA | |
| Methacrylic Acid SCHEMBL9775691 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCA4TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329446-B1 | FOR INK JET PRINTING; NONSMEARING | XEROX CORPORATION | 2001-12-11 | — | — | US | claimed |
| EP-0882771-A2 | Ink compositions | Xerox Corporation (US) | 1998-12-09 | — | — | EP | disclosed |