Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777981 | 0.86 | CYP4F2 (0.46) | MAPTLMNANPC1RAB9ACYP4F2 | |
| SCHEMBL9778026 | 0.76 | ADRB2 (0.47) | ADRB2ADRB1NPC1CYP4F2CYP4A11 | |
| SCHEMBL7296789 | 0.75 | ITGB3 (0.50) | — | |
| SCHEMBL22922181 | 0.75 | CYP4F2 (0.59) | MAPTLMNAEPHX2ADRB2ADRB1 | |
| SCHEMBL168856 | 0.75 | GSK3B (0.54) | MAPTLMNAL3MBTL1ADRB2ADRB1 | |
| SCHEMBL9294508 | 0.75 | THRA (0.55) | MAPTLMNAL3MBTL1ADRB2ADRB1 | |
| SCHEMBL23410286 | 0.75 | PLOD2 (0.61) | MAPTLMNANPC1RAB9A | |
| SCHEMBL9777993 | 0.75 | NPC1 (0.46) | MAPTLMNAL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9269810 | 0.74 | ITGB3 (0.49) | — | |
| SCHEMBL9264988 | 0.74 | EPHX2 (0.49) | MAPTEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |