Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410286 | 0.86 | PLOD2 (0.61) | NPC1RAB9APTPN1ALDH1A1POLB | |
| SCHEMBL940303 | 0.84 | MEN1 (0.52) | RAB9APTPN1ALDH1A1POLBKDM4E | |
| SCHEMBL10592529 | 0.81 | PLOD2 (0.39) | PTPN1NR1H4ALDH1A1POLBPLOD2 | |
| SCHEMBL21774348 | 0.80 | GSK3B (0.51) | RAB9AALDH1A1PLOD2MAPT | |
| SCHEMBL9778037 | 0.78 | EPHX2 (0.47) | NPC1RAB9ANR1H4ALDH1A1CASP3 | |
| SCHEMBL9837130 | 0.77 | PTPN1 (0.52) | NPC1RAB9APTPN1ALDH1A1BLM | |
| SCHEMBL9777981 | 0.77 | CYP4F2 (0.46) | NPC1RAB9AALDH1A1KDM4EGAA | |
| Methane SCHEMBL9835792 | 0.76 | NPC1 (0.50) | NPC1RAB9APTPN1ALDH1A1BLM | |
| SCHEMBL7436867 | 0.76 | HSD17B3 (0.52) | NPC1RAB9APTPN1NR1H4ALDH1A1 | |
| SCHEMBL1095373 | 0.76 | PLOD2 (0.72) | NPC1RAB9APTPN1ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |