Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.67 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 7/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014305 | 0.89 | MEP1B (0.60) | TBXA2RMEP1BEGFRERBB2L3MBTL1 | |
| SCHEMBL9777953 | 0.87 | MEP1B (0.61) | TBXA2RMEP1BEGFRERBB2KAT6A | |
| SCHEMBL9777971 | 0.87 | TBXA2R (0.59) | TBXA2RMAPTPRMT1 | |
| SCHEMBL9777954 | 0.85 | TBXA2R (0.55) | TBXA2RMEP1BEGFRERBB2L3MBTL1 | |
| SCHEMBL5899482 | 0.84 | L3MBTL1 (0.60) | TBXA2RMEP1BMAPTL3MBTL1KAT6A | |
| SCHEMBL9452076 | 0.84 | MEP1B (0.58) | TBXA2RMEP1BKAT6A | |
| SCHEMBL23014406 | 0.82 | EGFR (0.55) | MEP1BEGFRERBB2MAPTMMP1 | |
| SCHEMBL23014492 | 0.82 | KMT2A (0.59) | MEP1BEGFRERBB2MAPTL3MBTL1 | |
| Daltroban SCHEMBL309160 | 0.81 | TBXA2R (1.00) | TBXA2RMEP1BEGFRERBB2MAPT | |
| SCHEMBL2838364 | 0.79 | MMP1 (0.64) | MEP1BMAPTKAT6AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | claimed |
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |