Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.61 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777986 | 0.87 | TBXA2R (0.67) | MEP1BKAT6AMMP1TBXA2REGFR | |
| SCHEMBL5899544 | 0.86 | KAT6A (0.58) | MEP1BKAT6AMMP1GAAMMP12 | |
| SCHEMBL9777957 | 0.86 | ALDH1A1 (0.64) | KAT6AMMP1GAAMMP12TBXA2R | |
| SCHEMBL9452076 | 0.85 | MEP1B (0.58) | MEP1BKAT6ATBXA2R | |
| SCHEMBL9777990 | 0.85 | MEP1B (0.50) | MEP1BKAT6AMMP1GAAMMP12 | |
| SCHEMBL5899467 | 0.83 | KAT6A (0.72) | MEP1BKAT6AMMP1GAAMMP12 | |
| SCHEMBL7668876 | 0.82 | MMP1 (0.63) | MEP1BMMP1GAAMMP12KDM4E | |
| SCHEMBL11105032 | 0.81 | KEAP1 (0.71) | MEP1BTBXA2RKDM4EALDH1A1CXCR4 | |
| SCHEMBL10461554 | 0.79 | TBXA2R (0.76) | MEP1BTBXA2RALDH1A1TBXAS1 | |
| SCHEMBL23014260 | 0.78 | KAT6A (0.52) | MEP1BKAT6AMMP1GAAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | claimed |
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |