Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MMP12 | P39900 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014305 | 0.92 | MEP1B (0.60) | L3MBTL1FLT1FLT4KDRMEP1B | |
| SCHEMBL5899544 | 0.89 | KAT6A (0.58) | MEN1KMT2AMEP1BKAT6AGAA | |
| SCHEMBL2838364 | 0.88 | MMP1 (0.64) | MEP1BKAT6AMMP1MAPTMMP2 | |
| SCHEMBL23014492 | 0.85 | KMT2A (0.59) | L3MBTL1FLT1FLT4KDRKMT2A | |
| SCHEMBL23014406 | 0.85 | EGFR (0.55) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL23014361 | 0.84 | KAT6A (0.58) | MEN1KMT2AMEP1BKAT6AGAA | |
| SCHEMBL5320466 | 0.84 | ALDH1A1 (0.60) | L3MBTL1MEN1KMT2AKAT6AGAA | |
| SCHEMBL5899737 | 0.84 | MMP1 (0.63) | MEN1KMT2AMEP1BKAT6AGAA | |
| SCHEMBL9777986 | 0.84 | TBXA2R (0.67) | L3MBTL1FLT1FLT4KDRMEP1B | |
| SCHEMBL5899421 | 0.83 | KAT6A (0.65) | L3MBTL1FLT1FLT4KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | L3MBTL1 1816/4885FLT1 3175/4885FLT4 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.