Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777992 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL940303 | 0.79 | MEN1 (0.52) | SMN1; SMN2ALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL23410286 | 0.78 | PLOD2 (0.61) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9777993 | 0.78 | NPC1 (0.46) | NR1H4SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL2009205 | 0.77 | SMN1; SMN2 (0.51) | EPHX2NR1H4SMN1; SMN2ALOX15MAPT | |
| SCHEMBL21774348 | 0.76 | GSK3B (0.51) | EPHX2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8828412 | 0.74 | ALOX15 (0.59) | SMN1; SMN2ALOX15MAPTALDH1A1MEN1 | |
| SCHEMBL11658861 | 0.74 | FFAR1 (0.50) | EPHX2NR1H4SMN1; SMN2ALOX15MAPT | |
| SCHEMBL7294121 | 0.73 | ITGB3 (0.67) | EPHX2NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL10592529 | 0.73 | PLOD2 (0.39) | NR1H4SMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |