Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.38 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940303 | 0.82 | MEN1 (0.52) | PLOD2ALDH1A1SMN1; SMN2POLBPLOD3 | |
| SCHEMBL9777993 | 0.81 | NPC1 (0.46) | PLOD2ALDH1A1SMN1; SMN2POLBPTPN1 | |
| SCHEMBL23410286 | 0.81 | PLOD2 (0.61) | PLOD2ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL21774348 | 0.79 | GSK3B (0.51) | PLOD2ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL9778037 | 0.73 | EPHX2 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL27294641 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9777981 | 0.72 | CYP4F2 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28775880 | 0.72 | HPGD (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX12 | |
| SCHEMBL9777984 | 0.70 | MAPT (0.42) | LMNAMAPT | |
| SCHEMBL15904295 | 0.70 | MTNR1A (0.45) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |