Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342710 | 0.82 | SMN1; SMN2 (0.42) | PTGS2PTGS1ABCB1ALOX5SMN1; SMN2 | |
| SCHEMBL9342389 | 0.80 | SMN1; SMN2 (0.43) | PTGS2PTGS1TP53ALOX5SMN1; SMN2 | |
| SCHEMBL9778593 | 0.71 | PTGS2 (0.38) | PTGS2PTGS1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10584476 | 0.70 | ALDH1A1 (0.41) | TP53SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL9342270 | 0.70 | SMN1; SMN2 (0.46) | PTGS2PTGS1ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9341978 | 0.70 | SMN1; SMN2 (0.42) | PTGS2PTGS1ATMALOX5SMN1; SMN2 | |
| SCHEMBL31545311 | 0.70 | PPARA (0.46) | PTGS2 | |
| SCHEMBL10498179 | 0.70 | THRA (0.46) | — | |
| SCHEMBL9342747 | 0.70 | AKR1C3 (0.44) | PTGS2PTGS1ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9338406 | 0.69 | BCL2 (0.43) | PTGS2PTGS1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |