Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855050 | 0.98 | NR3C1 (0.57) | NR3C1PGRARESR2HTT | |
| SCHEMBL9778977 | 0.98 | NR3C1 (0.57) | NR3C1PGRARESR2HTT | |
| SCHEMBL9778880 | 0.91 | PGR (0.59) | NR3C1PGRARESR2HTT | |
| SCHEMBL9778780 | 0.89 | NR3C1 (0.53) | NR3C1PGRARESR2L3MBTL1 | |
| SCHEMBL8941546 | 0.88 | NR3C1 (0.53) | NR3C1PGRARESR2HTT | |
| SCHEMBL8941664 | 0.88 | NR3C1 (0.53) | NR3C1PGRARESR2HTT | |
| SCHEMBL9778897 | 0.87 | NR3C1 (0.55) | NR3C1PGRARESR2L3MBTL1 | |
| SCHEMBL30702473 | 0.86 | NR3C1 (0.54) | NR3C1PGRARESR2HTT | |
| SCHEMBL9779151 | 0.86 | HTT (0.54) | NR3C1PGRARESR2HTT | |
| SCHEMBL27579381 | 0.85 | LTA4H (0.59) | NR3C1PGRARESR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |