Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779447 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| SCHEMBL9779315 | 0.80 | MAPT (0.59) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| SCHEMBL9779393 | 0.79 | ADORA3 (0.51) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| SCHEMBL9779485 | 0.79 | ADORA3 (0.51) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| SCHEMBL9779277 | 0.79 | SCN9A (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL10377682 | 0.78 | KDM4E (0.58) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| SCHEMBL6137231 | 0.78 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4ERAB9ALMNA | |
| Fumaric Acid SCHEMBL10430887 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1TLR8TLR7 | |
| Fumaric Acid SCHEMBL9779268 | 0.77 | SCN9A (0.45) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| Fumaric Acid SCHEMBL9779264 | 0.77 | SCN9A (0.45) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |