Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779393 | 0.92 | ADORA3 (0.51) | ADORA3F11GABRG2GABRB3GABRA5 | |
| SCHEMBL9779299 | 0.82 | F11 (0.55) | F11ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9779236 | 0.79 | ALDH1A1 (0.48) | ADORA3F11ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9779447 | 0.76 | SMN1; SMN2 (0.45) | ADORA3F11ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2510353 | 0.76 | SMN1; SMN2 (0.65) | ADORA3ALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL21594770 | 0.75 | TDP1 (0.50) | ADORA3ALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9779442 | 0.74 | F11 (0.54) | F11GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21594758 | 0.74 | SMN1; SMN2 (0.53) | ADORA3GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29108575 | 0.74 | TDP1 (0.49) | ADORA3ALDH1A1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL10377682 | 0.72 | KDM4E (0.58) | ADORA3ALDH1A1L3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |