Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693687 | 0.88 | CTSK (0.38) | PTPRCCTSKCTSSRENTSHR | |
| SCHEMBL4152673 | 0.87 | TACR3 (0.40) | PTPRCCTSKCTSSRENTSHR | |
| SCHEMBL9769954 | 0.87 | ALOX5 (0.42) | ALOX5TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9779583 | 0.83 | ALDH1A1 (0.41) | ALOX5POLBNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL14217667 | 0.80 | CTSK (0.45) | ALOX5CTSKCTSSRENTSHR | |
| SCHEMBL5027594 | 0.80 | CTSK (0.45) | ALOX5CTSKCTSSRENTSHR | |
| Hydrochloric Acid SCHEMBL9326175 | 0.78 | ALOX5 (0.41) | ALOX5TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9779355 | 0.74 | CYP2C19 (0.43) | ALOX5TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11502413 | 0.74 | ALOX5 (0.45) | ALOX5CTSKCTSSTSHROPRM1 | |
| SCHEMBL2863369 | 0.72 | CES2 (0.41) | ALOX5CTSKCTSSRENCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |