Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 12/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780415 | 0.85 | FAAH (0.37) | CA2CA1CA9CA5ARORC | |
| SCHEMBL9780409 | 0.77 | KMT2A (0.34) | RORCMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL23929831 | 0.75 | LTA4H (0.37) | LTA4HMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL9780419 | 0.75 | KMT2A (0.34) | CA2CA1CA9CA5ARORC | |
| SCHEMBL8144722 | 0.75 | SMN1; SMN2 (0.39) | LTA4HMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL14058643 | 0.73 | TSHR (0.38) | RORCMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28613980 | 0.72 | ALDH1A1 (0.37) | RORCMEN1ALDH1A1KMT2A | |
| SCHEMBL9780413 | 0.69 | CA1 (0.33) | CA2CA1CA9CA5ARORC | |
| SCHEMBL4138448 | 0.69 | POLQ (0.36) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6428638 | 0.68 | ALDH1A1 (0.41) | CA2CA1CA9CA5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |