Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780419 | 0.70 | KMT2A (0.34) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL9780348 | 0.69 | LTA4H (0.38) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL23929830 | 0.67 | MLYCD (0.38) | KMT2AMEN1ALDH1A1TACR1TP53 | |
| SCHEMBL14058643 | 0.62 | TSHR (0.38) | KMT2AMEN1ALDH1A1RORCTSHR | |
| SCHEMBL3836196 | 0.62 | CCR5 (0.51) | CA1CA2CA9CA5ACCR5 | |
| SCHEMBL7421118 | 0.62 | CPA1 (0.43) | — | |
| SCHEMBL7421113 | 0.62 | CPA1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL28613980 | 0.61 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1RORCTSHR | |
| SCHEMBL6428638 | 0.61 | ALDH1A1 (0.41) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL9780409 | 0.61 | KMT2A (0.34) | KMT2AMEN1ALDH1A1NR1I2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |