Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 3/20 | 0.55 |
| ▸ | TK2 | O00142 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780910 | 1.00 | RNASE1 (0.58) | RNASE1TK1TK2 | |
| SCHEMBL9780799 | 0.90 | RNASE1 (0.46) | RNASE1TK1TK2 | |
| SCHEMBL9780789 | 0.90 | RNASE1 (0.46) | RNASE1TK1TK2 | |
| SCHEMBL31355237 | 0.89 | RNASE1 (0.72) | RNASE1TK1TK2 | |
| SCHEMBL9097516 | 0.87 | LMNA (0.63) | RNASE1TK1TK2 | |
| SCHEMBL9097523 | 0.87 | LMNA (0.63) | RNASE1TK1TK2 | |
| SCHEMBL9780593 | 0.86 | TK1 (0.62) | RNASE1TK1TK2 | |
| SCHEMBL9780588 | 0.86 | TK1 (0.62) | RNASE1TK1TK2 | |
| SCHEMBL9780827 | 0.85 | TK1 (0.44) | RNASE1TK1 | |
| SCHEMBL9780832 | 0.85 | TK1 (0.44) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |