Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 13/20 | 0.46 |
| ▸ | CDC25B | P30305 | 13/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 8/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876594 | 0.76 | PTPN1 (0.60) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL5397207 | 0.76 | PTPN1 (0.60) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL8877320 | 0.76 | PTPN1 (0.64) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL5968491 | 0.74 | PTPN1 (0.50) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL2172662 | 0.73 | PTPN1 (0.49) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL711126 | 0.72 | TSHR (0.42) | MAOBPARP15PARP10 | |
| SCHEMBL8877502 | 0.71 | PARP10 (0.58) | PTPN1MAOBPTPN2CDC25BPTPN6 | |
| SCHEMBL7239415 | 0.71 | MAOB (0.58) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL12443168 | 0.70 | PTPN1 (0.53) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL24302655 | 0.69 | ALDH1A1 (0.40) | MAOBPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794116-B1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA NV (BE) | 2015-06-03 | — | — | EP | disclosed |
| US-7875744-B2 | modulators of peroxisome proliferator activated receptors; treating diabetes, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cardiovascular diseases; dyslipidema; [4-[[2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]-acetic acid | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-25 | — | — | US | disclosed |
| US-20090318332-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | KUO GEE-HONG | 2009-12-24 | — | — | US | disclosed |
| EP-1794116-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006031969-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318332-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | PTPN1 335/4885MAOB 4169/4885PTPN2 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.