SCHEMBL18655950

SCHEMBL18655950

CN1CCCCN(OCc2ccccc2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.41
PREP P48147 1/20 0.40
LTA4H P09960 2/20 0.40
EGFR P00533 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4C Q9H3R0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19055901 0.79 ALDH1A1 (0.45) ALDH1A1TSHRPREPHTT
SCHEMBL9506098 0.78 L3MBTL1 (0.53) ALDH1A1TSHRPREPLTA4HHRH3
SCHEMBL28516086 0.76 L3MBTL1 (0.55) ALDH1A1PREPLTA4HHRH3
SCHEMBL6947156 0.76 CASP1 (0.53) ALDH1A1TSHRPREP
SCHEMBL23884962 0.73 ALDH1A1 (0.45) ALDH1A1TSHRPREP
SCHEMBL28467777 0.73 MEN1 (0.56) ALDH1A1TSHRPREPMEN1KMT2A
SCHEMBL9781753 0.73 EEF2K (0.42) ALDH1A1TSHR
SCHEMBL13386604 0.72 ALDH1A1 (0.55) ALDH1A1TSHR
SCHEMBL1446183 0.72 LTA4H (0.50) ALDH1A1TSHRLTA4HMEN1KMT2A
SCHEMBL1934716 0.71 ALDH1A1 (0.50) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281942-A1 B-LACTAMASE INHIBITOR AND APPLICATION THEREOF Xuanzhu Pharma Co., Ltd. (CN) 2018-02-14 EP disclosed
WO-2017045510-A1 Β-LACTAMASE INHIBITOR AND APPLICATION THEREOF 山东轩竹医药科技有限公司 2017-03-23 WO disclosed