Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978250 | 1.00 | CYP11B1 (0.32) | CYP11B1CYP11B2LMNAKMT2ACACNA1B | |
| SCHEMBL974948 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL974947 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL976634 | 0.76 | L3MBTL1 (0.34) | KMT2ACACNA1B | |
| SCHEMBL1223403 | 0.75 | CYP11B1 (0.31) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL1223400 | 0.75 | CYP11B1 (0.31) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL978102 | 0.73 | ALDH1A1 (0.38) | KMT2A | |
| SCHEMBL978630 | 0.73 | — | — | |
| SCHEMBL6184438 | 0.72 | MAOB (0.34) | LMNA | |
| SCHEMBL6184434 | 0.72 | MAOB (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188009-B2 | 4-(3-aminobenzoyl)-5-cyclopropylisoxazoles effective as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2260027-B1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-29 | — | — | EP | disclosed |
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-01-20 | — | — | US | disclosed |
| EP-2260027-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | Bayer CropScience AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118125-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |
| EP-2105437-A1 | 4-(3-Aminobenzoyl)-5-cyclopropylisoxazols as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2009-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | CYP4X1, PRDX4, PRDX5 | CYP11B1 220/4885CYP11B2 272/4885LMNA 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.