Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783820 | 0.81 | HSD11B1 (0.32) | HSD11B1P2RX7GRM4GPBAR1HSP90AA1 | |
| SCHEMBL9783707 | 0.77 | KCNA5 (0.37) | HSD11B1P2RX7L3MBTL1 | |
| SCHEMBL9783945 | 0.76 | CYP19A1 (0.43) | LMNACYP19A1P2RX7CYP11B1CYP11B2 | |
| SCHEMBL9783826 | 0.70 | GPBAR1 (0.36) | LMNATP53PSEN1PSEN2APH1B | |
| SCHEMBL11777500 | 0.69 | MAPK14 (0.40) | TP53GPBAR1HSP90AA1HSP90AB1 | |
| SCHEMBL9783934 | 0.66 | CYP19A1 (0.35) | HSD11B1CYP19A1GRM4GPBAR1GRM5 | |
| SCHEMBL9783983 | 0.65 | ALDH1A1 (0.39) | HSD11B1LMNACYP19A1P2RX7CYP11B1 | |
| SCHEMBL9784031 | 0.64 | CYP11B1 (0.40) | LMNAP2RX7GPBAR1CYP11B1CYP11B2 | |
| SCHEMBL9783676 | 0.64 | HSD11B1 (0.34) | HSD11B1P2RX7GRM5GABRG2GABRB3 | |
| SCHEMBL13145112 | 0.64 | HSP90AA1 (0.53) | LMNAHSP90AA1HSP90AB1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |