Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 8/20 | 0.51 |
| ▸ | CTSL | P07711 | 7/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244458 | 1.00 | CTRB1 (0.52) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL10448480 | 0.89 | CTSS (0.56) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL7169930 | 0.87 | CTRB1 (0.54) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL4598612 | 0.87 | CTRB1 (0.61) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL7172190 | 0.87 | CTRB1 (0.54) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL7298020 | 0.87 | CTRB1 (0.54) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL7300784 | 0.87 | CTRB1 (0.61) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL7310119 | 0.87 | CTRB1 (0.61) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL9313747 | 0.85 | CASP1 (0.54) | CTRB1CTSSCTSLTACR1CTSK | |
| SCHEMBL4256367 | 0.85 | CTSS (0.55) | CTRB1CTSSCTSLTACR1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0094815-A2 | Oligopeptide prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1983-11-23 | — | — | EP | disclosed |