Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968847 | 0.94 | FAAH (0.62) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL464534 | 0.94 | FAAH (0.62) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Ethyl Oleate SCHEMBL8518936 | 0.88 | HSD17B10 (0.65) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Ethyl Oleate SCHEMBL8518938 | 0.88 | HSD17B10 (0.65) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL1007457 | 0.88 | TERT (0.58) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL27135814 | 0.88 | TERT (0.58) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL28413969 | 0.86 | TERT (0.56) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL28978390 | 0.86 | TERT (0.56) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL1644404 | 0.86 | TERT (0.56) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL325124 | 0.86 | TERT (0.56) | FAAHHSD17B10CYP3A4ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072015-A | Neutralization, hydrolysis | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-12-10 | — | — | US | disclosed |