Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968847 | 1.00 | FAAH (0.62) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| Sulfuric Acid SCHEMBL9787798 | 0.94 | FAAH (0.56) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL2429250 | 0.90 | TERT (0.61) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL28455083 | 0.90 | TERT (0.61) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL9069822 | 0.90 | TERT (0.61) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL9069802 | 0.90 | TERT (0.61) | FAAHHSD17B10CYP3A4ALOX15TDP1 | |
| SCHEMBL382296 | 0.90 | DGKA (0.59) | ALDH1A1TSHRDGKAMAPTKMT2A | |
| SCHEMBL6890027 | 0.90 | DGKA (0.59) | ALDH1A1TSHRDGKAMAPTKMT2A | |
| SCHEMBL3327698 | 0.90 | DGKA (0.59) | ALDH1A1TSHRDGKAMAPTKMT2A | |
| SCHEMBL27396784 | 0.90 | DGKA (0.59) | ALDH1A1TSHRDGKAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170036990-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS AG (DE) | 2017-02-09 | — | — | US | disclosed |
| US-9486538-B2 | Lipids, lipid complexes and use thereof | SILENCE THERAPEUTICS GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| US-20150359906-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS AG (DE) | 2015-12-17 | — | — | US | disclosed |
| US-9125820-B2 | Lipids, lipid complexes and use thereof | SILENCE THERAPEUTICS GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-20140329885-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS GMBH (DE) | 2014-11-06 | — | — | US | disclosed |
| US-8735453-B2 | Lipids, lipid complexes and use thereof | SILENCE THERAPEUTICS GMBH (DE) | 2014-05-27 | — | — | US | disclosed |
| US-20130165381-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS AG (DE) | 2013-06-27 | — | — | US | disclosed |
| US-8357722-B2 | Lipids, lipid complexes and use thereof | Silence Therpeutics AG (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20120065138-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20110294871-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-8017804-B2 | Lipids, lipid complexes and use thereof | SILENCE THERAPEUTICS AG (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20080274116-A1 | Lipids, Lipid Complexes and Use Thereof | SILENCE THERAPEUTICS AG (DE) | 2008-11-06 | — | — | US | disclosed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065138-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, SGMS1 | FAAH 167/4885HSD17B10 122/4885CYP3A4 646/4885 |
| US-20110294871-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, SGMS1 | FAAH 167/4885HSD17B10 122/4885CYP3A4 646/4885 |
| US-20130165381-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, LIPC | FAAH 185/4885HSD17B10 175/4885CYP3A4 538/4885 |
| US-20170036990-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, LIPC | FAAH 185/4885HSD17B10 175/4885CYP3A4 538/4885 |
| US-20150359906-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, LIPC | FAAH 185/4885HSD17B10 175/4885CYP3A4 538/4885 |
| US-20080274116-A1 | Lipids, Lipid Complexes and Use Thereof | MGLL, LIPA, SGMS1 | FAAH 153/4885HSD17B10 109/4885CYP3A4 559/4885 |
| US-20140329885-A1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | MGLL, LIPA, LIPC | FAAH 185/4885HSD17B10 175/4885CYP3A4 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.