Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | EPM2A | O95278 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788999 | 0.85 | RAB9A (0.50) | ADORA3EGFRMEN1KMT2ANPC1 | |
| SCHEMBL9788042 | 0.84 | MAPT (0.56) | ADORA3ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL9789067 | 0.78 | LMNA (0.40) | ADORA3ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL9789051 | 0.76 | ADORA3 (0.48) | ADORA3ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL9789038 | 0.73 | CA1 (0.52) | ADORA3EGFRMEN1KMT2AMAPT | |
| SCHEMBL9789114 | 0.72 | ADORA3 (0.44) | ADORA3MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL9789019 | 0.71 | KMT2A (0.44) | ALOX5MEN1KMT2ANPC1MAPT | |
| SCHEMBL6153975 | 0.69 | ROCK2 (0.62) | EGFRPTGESALOX5MEN1KMT2A | |
| SCHEMBL8298036 | 0.68 | PIN1 (0.72) | EGFR | |
| SCHEMBL9788026 | 0.68 | NPC1 (0.36) | ADORA3MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2078672-A | — | — | None | — | — | JP | disclosed |
| US-5075326-A | Fungicides, microbiocides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |
| US-5071865-A | Fungicides, bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0402716-A1 | 2-Acylamino-4-halogeno-5-nitrothiazole derivatives, process for their preparation, their use in pesticides and new intermediate products | BAYER AG (DE) | 1990-12-19 | — | — | EP | disclosed |
| US-4962102-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| JP-H0278672-A | 4-HALOGENO-5-NITROTHIAZOLE DERIVATIVE, ITS PRODUCTION AND NOVEL INTERMEDIATE USED AS HARMFUL ORGANISM CONTROL AGENT | BAYER AG | 1990-03-19 | — | — | JP | disclosed |
| EP-0351662-A2 | 4-Halo-5-nitrothiazole derivatives, process for their preparation, their use as pesticides, and intermediates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |