Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788244 | 0.87 | NR4A3 (0.53) | ALDH1A1RAB9ASMN1; SMN2POLBLMNA | |
| SCHEMBL10813419 | 0.81 | RAB9A (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL9788265 | 0.81 | NR4A3 (0.41) | ALDH1A1RAB9ASMN1; SMN2POLBLMNA | |
| SCHEMBL10358133 | 0.81 | BCL2 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL9788326 | 0.80 | MAPK14 (0.45) | LMNANR4A3NPBWR1MAPK14KEAP1 | |
| SCHEMBL9788253 | 0.80 | NR4A3 (0.56) | ALDH1A1RAB9APOLBLMNANR4A3 | |
| SCHEMBL9788315 | 0.77 | AGTR1 (0.40) | ALDH1A1SMN1; SMN2POLBLMNANR4A3 | |
| SCHEMBL9788295 | 0.76 | LMNA (0.43) | ALDH1A1SMN1; SMN2LMNANR4A3GAA | |
| SCHEMBL9788330 | 0.75 | NR4A3 (0.42) | ALDH1A1RAB9APOLBLMNANR4A3 | |
| SCHEMBL9788273 | 0.74 | NR4A3 (0.67) | ALDH1A1RAB9ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |