Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064647 | 0.92 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7061571 | 0.83 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29457308 | 0.81 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5610739 | 0.78 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9547590 | 0.77 | ALOX15 (0.38) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL19019800 | 0.77 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6829110 | 0.76 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19019783 | 0.76 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL30827212 | 0.76 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29831625 | 0.75 | ALDH1A1 (0.37) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063257-A | DENTAL GLASS IONOMER CEMENT COMPOSITIONS | G-C DENTAL INDUSTRIAL CORP. (JP) | 1991-11-05 | — | — | US | disclosed |