Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1597063 | 0.86 | CYP1A2 (0.48) | ESR1ESR2CYP2C9CYP2C19RPS6KA3 | |
| SCHEMBL133408 | 0.78 | ESR1 (0.58) | ESR1ESR2PDCD1CD274CYP2C9 | |
| SCHEMBL1596154 | 0.75 | SHBG (0.37) | ESR1ESR2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1594695 | 0.71 | CYP1A2 (0.39) | CYP2C9CYP2C19ALOX15HIF1ACYP1A2 | |
| SCHEMBL4630558 | 0.71 | ESR1 (0.50) | ESR1ESR2PDCD1CD274CYP2C9 | |
| SCHEMBL4471799 | 0.71 | ADRB2 (0.39) | ESR1ESR2RPS6KA3CA3CA5A | |
| SCHEMBL13104729 | 0.70 | ESR1 (0.67) | ESR1ESR2RPS6KA3MEN1KMT2A | |
| SCHEMBL30343458 | 0.70 | SHBG (0.55) | ESR1ESR2HIF1AHSD17B10ALOX12 | |
| SCHEMBL1597362 | 0.70 | SHBG (0.55) | ESR1ESR2HIF1AHSD17B10ALOX12 | |
| SCHEMBL834372 | 0.70 | RPS6KA3 (0.39) | ESR1ESR2RPS6KA3PTGS1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032629-A | Comprising the reaction product of an polyalkylenepolyether and a polyepoxy compound; discoloration inhibition; hydraulics; shelf life | RUTGERSWERKE AG (DE) | 1991-07-16 | — | — | US | disclosed |