Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791099 | 1.00 | BACE1 (0.50) | BACE1ALOX5PTGS1PTGS2PTGER1 | |
| SCHEMBL2433472 | 0.79 | PTGER3 (0.66) | BACE1PTGER1PTGER3PTGER2MEN1 | |
| SCHEMBL181054 | 0.79 | PTGER3 (0.66) | BACE1PTGER1PTGER3PTGER2MEN1 | |
| SCHEMBL30317554 | 0.79 | BACE1 (0.58) | BACE1PTGER1PTGER3PTGER2SMN1; SMN2 | |
| SCHEMBL17833498 | 0.78 | TRPM8 (0.47) | ALOX5PTGS1PTGS2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11527565 | 0.78 | PTGER3 (0.64) | BACE1PTGER1PTGER3PTGER2MEN1 | |
| SCHEMBL9877155 | 0.77 | HDAC2 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL13697272 | 0.77 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 | |
| SCHEMBL3667411 | 0.76 | BACE1 (0.55) | BACE1PTGER1PTGER3PTGER2MEN1 | |
| SCHEMBL6835913 | 0.76 | BACE1 (0.55) | BACE1PTGER1PTGER3PTGER2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |