Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732406 | 0.87 | TRPM8 (0.48) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL19954281 | 0.87 | TRPM8 (0.48) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL13697272 | 0.81 | ALOX5 (0.46) | TRPM8ALOX5PTGS1PTGS2LMNA | |
| SCHEMBL28379416 | 0.79 | NPC1 (0.63) | TRPM8ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL5598952 | 0.79 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9AKDM4EGMNN | |
| SCHEMBL5598954 | 0.79 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9AKDM4EGMNN | |
| SCHEMBL3363365 | 0.78 | ALOX5 (0.73) | TRPM8ALOX5PTGS1PTGS2 | |
| SCHEMBL9877248 | 0.78 | HDAC8 (0.58) | ALDH1A1RAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL3363362 | 0.78 | ALOX5 (0.73) | TRPM8ALOX5PTGS1PTGS2 | |
| SCHEMBL9791099 | 0.78 | BACE1 (0.50) | ALOX5PTGS1PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | LIPA, HRH2, HRH1 | TRPM8 1059/4885ALOX5 25/4885PTGS1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.