Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9469543 | 0.98 | AOC1 (0.39) | AOC1AOC3MAPTALDH1A1GAA | |
| SCHEMBL7608055 | 0.78 | TGFBR1 (0.38) | TGFBR1 | |
| SCHEMBL9470270 | 0.71 | ALDH1A1 (0.57) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9330010 | 0.71 | — | — | |
| SCHEMBL2046959 | 0.70 | — | — | |
| SCHEMBL30074192 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27703391 | 0.68 | AOC1 (0.53) | AOC1AOC3MAPTALDH1A1GAA | |
| SCHEMBL19851075 | 0.68 | MAPT (0.59) | MAPTALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL3958329 | 0.68 | MAPT (0.59) | MAPTALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL16089617 | 0.68 | PLAU (0.44) | AOC1AOC3MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | claimed |
| US-5039687-A | Learning enhancement, cognition activation | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5032599-A | Learning enhancement | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| US-4752610-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | disclosed |