Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792211 | 0.80 | SRD5A2 (0.50) | HPGDKMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL11859212 | 0.78 | HPGD (0.56) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL9792295 | 0.77 | MEN1 (0.50) | KMT2ARAB9AMEN1CES2CES1 | |
| SCHEMBL7676938 | 0.76 | MAPT (0.52) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL51509 | 0.75 | RXFP1 (0.79) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL9418310 | 0.75 | RXFP1 (0.79) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL11813331 | 0.75 | CA1 (0.49) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL2466074 | 0.74 | HPGD (1.00) | HPGDKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL9792275 | 0.73 | ALDH1A1 (0.37) | KMT2ARAB9AMEN1MAPK1ALDH1A1 | |
| SCHEMBL7685125 | 0.73 | RAB9A (0.53) | HPGDKMT2AMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988822-A | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4873340-A | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-10-10 | — | — | US | disclosed |