Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004102 | 0.86 | NPC1 (0.56) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL1538312 | 0.85 | NPC1 (0.47) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL30375905 | 0.85 | NPC1 (0.47) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL18003523 | 0.82 | NPC1 (0.52) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL761993 | 0.81 | MEN1 (0.52) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL25054159 | 0.78 | NPC1 (0.45) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL4432370 | 0.76 | NPC1 (0.59) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL264940 | 0.75 | NPC1 (0.55) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL10235035 | 0.75 | RAB9A (0.42) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL20991103 | 0.75 | NPC1 (0.42) | NPC1RAB9AMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| EP-1931659-B1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2010-09-08 | — | — | EP | claimed |
| US-7655679-B2 | Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions | SANOFI-AVENTIS (FR) | 2010-02-02 | — | — | US | claimed |
| CN-101277953-A | Atives of 2-aminthiazoles and 2-aminooxazoles, processes for their preparation and their use as pharmaceuticals | SANOFI AVENTIS (FR) | 2008-10-01 | — | — | CN | claimed |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | US | claimed |
| EP-1931659-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | claimed |
| WO-2007039176-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | claimed |
| US-12622896-B2 | Antiviral compounds, compositions and methods of use | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-05-12 | — | — | US | disclosed |
| WO-2026090589-A1 | HETEROCYCLIC HBS1L DEGRADERS | TANGO THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4406957-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2026-04-08 | — | — | EP | disclosed |
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2026-03-17 | — | — | US | disclosed |
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | GENENTECH, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| CN-119677735-A | Benzothiazole compounds as VHL ligands | 基因泰克公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | US | disclosed |
| US-20080207905-A1 | Metallic Compound and Organic Electroluminescence Device Comprising the Same | SAMSUNG ELECTRONICS CO., LTD., (KR) | 2008-08-28 | — | — | US | disclosed |
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1931659-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007078180-A1 | METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007039176-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |
| US-4179296-A | CONTAINING A BENZIMIDAZOLOCARBOCYANINE DYE AND AT LEAST ONE OTHER CYANINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, ARNT | NPC1 3205/4885RAB9A 4214/4885MEN1 4746/4885 |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | PPARA, PPARD, PPARG | NPC1 3355/4885RAB9A 4608/4885MEN1 4730/4885 |
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | VHL, BRCA1, GLS | NPC1 288/4885RAB9A 2053/4885MEN1 2564/4885 |
| US-20080207905-A1 | Metallic Compound and Organic Electroluminescence Device Comprising the Same | NOX5, PRMT5, SIRT5 | NPC1 4183/4885RAB9A 1882/4885MEN1 470/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | NPC1 917/4885RAB9A 1863/4885MEN1 722/4885 |
| US-12622896-B2 | Antiviral compounds, compositions and methods of use | SARS1, NSUN2, ZC3HAV1 | NPC1 30/4885RAB9A 3269/4885MEN1 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.