Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.32 |
| ▸ | GABRP | O00591 | 4/20 | 0.32 |
| ▸ | GABRD | O14764 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.32 |
| ▸ | GABRE | P78334 | 4/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830708 | 0.78 | HTT (0.52) | RORCHTTIDO1ALDH1A1HPGD | |
| SCHEMBL980011 | 0.75 | GABRA2 (0.38) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL2863488 | 0.70 | RORC (0.52) | RORCHTTALDH1A1HPGDMAPT | |
| SCHEMBL6975897 | 0.63 | GABRB3 (0.45) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL15697514 | 0.62 | JAK2 (0.54) | RORCRORBMEN1ALDH1A1KMT2A | |
| SCHEMBL30094862 | 0.62 | JAK2 (0.54) | RORCRORBMEN1ALDH1A1KMT2A | |
| SCHEMBL10676858 | 0.61 | GABRB3 (0.43) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL10678078 | 0.59 | GABRA2 (0.40) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL979677 | 0.59 | MAPK1 (0.53) | HTTIDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL10679158 | 0.59 | GABRA2 (0.38) | HTTGABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS PESTICIDES | DDT, TYR, CAT | RORC 2101/4885RORB 3163/4885HTT 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.